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  • 產(chǎn)品名稱：兔抗STAT3多克隆抗體

  • 產(chǎn)品型號：100ul
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：1560
  • 產(chǎn)品庫存：60
  • 產(chǎn)品文檔：
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簡單介紹：
隨著近幾年生物、生命科學(xué)的發(fā)展，抗體試劑的供應(yīng)商也越來越多，兔抗STAT3多克隆抗體作為國內(nèi)生物試劑和消耗品的知名企業(yè)，上海通蔚生物有限公司不僅見證了行業(yè)的發(fā)展，也在發(fā)展的洪流中找準(zhǔn)了自己的位置，逆流而上，揚(yáng)帆遠(yuǎn)航。
詳情介紹：

中文名稱：  兔抗STAT3多克隆抗體  

英文名稱： Anti-STAT3 rabbit polyclonal antibody

別      名： signal transducer and activator of transcription 3; APRF; HIES; ADMIO; ADMIO1

相關(guān)類別： 一抗

抗      原： STAT3

儲      存： 冷凍（-20℃）

宿      主： Rabbit

反應(yīng)種屬： Human, Mouse, Rat

標(biāo) 記 物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

The Stat3 transcription factor is an important signaling molecule for many cytokines and growth factor receptors and is required for murine fetal development. Research studies have shown that Stat3 is constitutively activated in a number of human tumors and possesses oncogenic potential and anti-apoptotic activities. Stat3 is activated by phosphorylation at Tyr705, which induces dimerization, nuclear translocation, and DNA binding. Transcriptional activation seems to be regulated by phosphorylation at Ser727 through the MAPK or mTOR pathways. Stat3 isoform expression appears to reflect biological function as the relative expression levels of Stat3α (86 kDa) and Stat3β (79 kDa) depend on cell type, ligand exposure, or cell maturation stage. It is notable that Stat3β lacks the serine phosphorylation site within the carboxy-terminal transcriptional activation domain.

Applications:

ELISA, WB

Name of antibody:

STAT3

Immunogen:

Fusion protein of human STAT3

Full name:

signal transducer and activator of transcription 3

Synonyms:

APRF; HIES; ADMIO; ADMIO1

SwissProt:

P40763

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

88 kDa

WB Positive control:

HepG2 cell lysate

WB Recommended dilution:

200-1000


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