中文名稱: ARHGEF9抗原(重組蛋白)
英文名稱: ARHGEF9 Antigen (Recombinant Protein)
別 名: PEM2; EIEE8; PEM-2; HPEM-2; COLLYBISTIN
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 103-287 amino acids of human ARHGEF9
技術(shù)規(guī)格
Full name:
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Cdc42 guanine nucleotide exchange factor (GEF)
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Synonyms:
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PEM2; EIEE8; PEM-2; HPEM-2; COLLYBISTIN
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Swissprot:
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O43307
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Gene Accession:
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BC117406
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Purity:
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>85%, as determined by Coomassie blue stained SDS-PAGE
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Expression system:
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Escherichia coli
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Tags:
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His tag C-Terminus, GST tag N-Terminus
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Background:
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The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.
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